Available from Fluidigm Europe - a recent independent feature in Technology Review Magazine calls Fluidigm's technology "a fundamental breakthrough in how researchers can interact with the biological world".
The Fluidigm BioMark™ System revolutionizes how biologists can conduct single-cell gene expression experiments. Using microfluidic chips, the BioMark System features low input requirements and provides the sensitivity and assay throughput necessary for qPCR. Using standard TaqMan® and DNA binding dye assays, Fluidigm's proprietary Integrated Fluidic Circuit (IFC) technology enables single-cell discovery with the ability to screen hundreds of genes from single cells. Now with this unique technology it is possible to conduct up to 36,000 PCR reactions in one day, with one technician, and one BioMark System.
For a copy of the Technology Review Magazine feature article please contact Fluidigm Europe on +33 160 92 42 40 or email eve.marquis@fluidigm.com.
Designed for gene expression studies and digital PCR, the BioMark System sets the new standard for high-throughput real-time qPCR assays, integrating thermal cycling and fluorescence detection on Digital Array™ IFCs and Dynamic Array™ IFCs.
Fluidigm technology is based on the Integrated Fluidic Circuit (IFC) systems that significantly improve productivity in life science research. Fluidigm's IFCs enable the simultaneous performance of PCR reactions in nanoliter volumes. These "integrated circuits for biology" are made possible by miniaturizing and integrating liquid handling components on a single microfluidic device. Fluidigm's systems, consisting of instrumentation, software and single-use chips, increase throughput, decrease costs and enhance sensitivity compared to conventional laboratory systems.
The BioMark System consists of a real-time PCR instrument, the Dynamic Array IFCs for multiplexing the samples and reagents, as well as an IFC loader to load the IFCs.
Fluidigm develops, manufactures and markets proprietary Integrated Fluidic Circuit (IFC) systems that significantly improve productivity in life science research. Fluidigm IFCs enable the simultaneous performance of thousands of sophisticated biochemical measurements in extremely minute volumes. These "integrated circuits for biology" are made possible by miniaturizing and integrating liquid handling components on a single microfluidic device. Fluidigm systems, consisting of instrumentation, software and chips, increase throughput, decrease costs and enhance sensitivity compared to conventional laboratory systems.
This blog has been set up for editors, reviewers, authors and readers of Elsevier's Analytical Chemistry Journals - all of which can be seen below. It will be updated from Monday to Friday with general news and announcements concerning the titles listed on this page. It should be noted that the views or claims made in the news items and feeds are not necessarily those of the Publisher.
World Congress on Biosensors 2014
Biosensors 2014
Friday, 7 January 2011
Thursday, 6 January 2011
Ideal controls for PCR, RNA microarray & antibody array studies
The AMSBIO range of Universal Reference Products (RNA, cDNA and Protein Lysate) has been expanded to include standards for studies involving humans as well as for animal species including Monkey, Dog, Mouse, Rat, and Chicken. These products provide ideal controls for high throughput PCR, RNA microarray and antibody array studies.
All AMSBIO Universal Reference Products are derived from very diverse tissue sets (from both male and female donors), and manufactured on an industrial scale, to ensure the broadest coverage of genes and to minimize the lot-to-lot variation.
Universal RNA from AMSBIO is total RNA isolated from sources, by modified guanidine thiocyanate techniques. Universal RNA can be used as controls for optimizing and trobleshooting single and two colour microarray studies. Universal cDNA is prepared by reverse transcribing AMSBIO's Universal RNA by random hexamer or oligo dT primer. Total RNA is isolated by modified guanidine thiocyanate techniques. Universal cDNA from AMSBIO can be used as controls for real time PCR and regular PCR, and also as gene pools for cloning genes. Universal Protein Lysate from AMSBIO is total protein isolated from whole tissue sources. Universal Protein Lysate can be used as controls for comparison of protein expression and antibody microarray studies.
For further information on Universal Reference products please visit http://www.amsbio.com/Ideal-controls-for-PCR-RNA-microarray-and-antibody-array-studies.aspx or contact AMSBIO on +44-1235-828200 / email info@amsbio.com.
All AMSBIO Universal Reference Products are derived from very diverse tissue sets (from both male and female donors), and manufactured on an industrial scale, to ensure the broadest coverage of genes and to minimize the lot-to-lot variation.
Universal RNA from AMSBIO is total RNA isolated from sources, by modified guanidine thiocyanate techniques. Universal RNA can be used as controls for optimizing and trobleshooting single and two colour microarray studies. Universal cDNA is prepared by reverse transcribing AMSBIO's Universal RNA by random hexamer or oligo dT primer. Total RNA is isolated by modified guanidine thiocyanate techniques. Universal cDNA from AMSBIO can be used as controls for real time PCR and regular PCR, and also as gene pools for cloning genes. Universal Protein Lysate from AMSBIO is total protein isolated from whole tissue sources. Universal Protein Lysate can be used as controls for comparison of protein expression and antibody microarray studies.
For further information on Universal Reference products please visit http://www.amsbio.com/Ideal-controls-for-PCR-RNA-microarray-and-antibody-array-studies.aspx or contact AMSBIO on +44-1235-828200 / email info@amsbio.com.
Just Published: Journal of Chromatography A
A new issue of the above journal has just been published. To see abstracts of the papers it contains (with links through to the full papers) click here:
Oxford Instruments ships impressive five module cluster tool for growing PV market
Leading system manufacturer Oxford Instruments Plasma Technology has recently shipped a five module cluster system to Robert Bosch, one of the world’s leading manufacturers of solar cells. The System100Pro deposition tool is a ‘Hex Handler’ providing capabilities for several deposition technologies, and allowing multiple process steps to be carried out without a vacuum break.
Oxford Instruments’ cluster systems offer high vacuum options for the handler and process modules, resulting in reduced background contamination levels, and the ability to cluster different deposition technologies. The system delivered to Bosch also incorporates a high temperature substrate table option up to 700ºC, and flexibility of power ramping within the software, and low power plasma strike options, thus minimising potential damage at the start of process. Some of the technology was developed under the EC supported contract FP7-Energy-2009-1 - 241281 'ThinSi'.
Mark Vosloo, Sales and Customer Support Director, Oxford Instruments Plasma Technology comments, “This five module tool for such a prestigious customer has allowed us to successfully integrate multiple technologies into the cluster, such as the ability to run both ALD and plasma CVD aluminium oxide depositions. With the increasing trend towards generating energy by renewable means, we are establishing ourselves as a key supplier to the growing PV R&D market.”
Based in Stuttgart , Germany
Wednesday, 5 January 2011
Miniature NMR Spectroscopy Solution
Mestrelab Research, SL and picoSpin, LLC have announced plans to include a free, one-year single-user license for Mnova NMR software with every picoSpin-45 NMR spectrometer. Customers will be able to activate the Mnova NMR license immediately after receiving the picoSpin-45.
Carlos Cobas, President of Mestrelab Research SL, commented “At Mestrelab, we are very excited by the picoSpin-45 technology and its potential to make NMR accessible to many people who may not have had the capability to use it before. Mnova is focused on ease of use and flexibility and on taking NMR processing to every desktop, and we think both products are a perfect fit, so we are delighted to bundle up our software with the picoSpin spectrometers to give their users the best possible experience when handling their newly generated NMR data. We look forward to a long term association with picoSpin and its customers and will be releasing future products for this specific user base.”
“The Mnova NMR analysis package complements perfectly our miniature NMR spectrometer,” said John Price, president and chief scientist of picoSpin, LLC. He added, “Both products emphasize ease-of-use, power and flexibility. Although picoSpin-45 data can be handled by most NMR analysis packages, we think bundling our product with Mnova is the best way to make sure our customers have a great out-of-the-box experience.” Many examples of picoSpin-45 spectra analyzed with MNova can be found now on the company’s web site at http://www.picospin.com/applications, and picoSpin plans to feature Mnova NMR in the Getting Started Guide for the picoSpin-45. Orders for the picoSpin-45 can be placed now and shipments to customers will start in March 2011.
Carlos Cobas, President of Mestrelab Research SL, commented “At Mestrelab, we are very excited by the picoSpin-45 technology and its potential to make NMR accessible to many people who may not have had the capability to use it before. Mnova is focused on ease of use and flexibility and on taking NMR processing to every desktop, and we think both products are a perfect fit, so we are delighted to bundle up our software with the picoSpin spectrometers to give their users the best possible experience when handling their newly generated NMR data. We look forward to a long term association with picoSpin and its customers and will be releasing future products for this specific user base.”
“The Mnova NMR analysis package complements perfectly our miniature NMR spectrometer,” said John Price, president and chief scientist of picoSpin, LLC. He added, “Both products emphasize ease-of-use, power and flexibility. Although picoSpin-45 data can be handled by most NMR analysis packages, we think bundling our product with Mnova is the best way to make sure our customers have a great out-of-the-box experience.” Many examples of picoSpin-45 spectra analyzed with MNova can be found now on the company’s web site at http://www.picospin.com/applications, and picoSpin plans to feature Mnova NMR in the Getting Started Guide for the picoSpin-45. Orders for the picoSpin-45 can be placed now and shipments to customers will start in March 2011.
New AQUACOUNTER® Karl Fischer Volumetric Titrator
JM Science has announced their new AQUACOUNTER® Karl Fischer Volumetric Titrator (AQV-2200S). This high-end titrator is the perfect choice for a very wide range from 100 ppm to 100% water content with is maximum capability for automation and future up-gradability.
This new titrator is ideal for users who: 1) have many kinds of samples to be analyzed; 2) exchange KF reagents frequently or after each measurement; 3) are eco-minded and budget-conscious.
Small volume titration cell requires only 20mL of titration solvent for accurate measurements. Less reagent volume reduces waste and is easy to replace with fresh solvent for the next measurement. Combining one additional KF station with either a volumetric or coulometric module enables two different measurements to be performed at the same time. With both a volumetric and coulometric channel, one can measure moisture over the entire range from 1ppm to 100% or double your sample throughput with 2 identical KF stations.
A two-channel option means easy “plug-and-play”. End-users can add various peripherals, such as a second channel, and the system recognizes the new channels and begins working with them immediately. Current status, data and function keys are displayed on a colorful and large screen. Color touch screen is 7.5-inches wide. All helpful and necessary information is always at hand! Result data with curves can be viewed on your PC internet browsing program without optional software. Save and load parameters and results via USB flash memory. Built-in thermal printer has easy paper loading and high resolution printouts.
For more information contact us at 1-800-495-1678 or visit us at www.jmscience.com
Genevac's technical eNewsletter.
Genevac has announced the availability of the Winter 2010 edition of its informative technical eNewsletter.
Accessible as a pdf download (www.genevac.org/newsletter.htm) the main feature of the new issue focuses upon how to optimise, adjust and control methods on modern centrifugal evaporators. Also in this edition the phenomenon known as "cryopumping" (where a condenser removes vapour from the evaporator chamber to maintain the vacuum level, thereby enabling more vapour to be removed) is discussed.
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