Fluidigm has published the Fall 2011 edition of its Community eNewsletter. The Fluidigm Community eNewsletter is an informative publication dedicated to providing an insight into the latest innovations in integrated fluidic circuit (IFC) technology and topical applications development which will be of interest to researchers involved with gene expression, SNP genotyping and sample preparation for next generation sequencing.
In this new issue, researchers from the Emory University School of Medicine, Atlanta, Georgia and the Sanford-Burnham Medical Research Institute, La Jolla, California report upon how they have used next-generation sequencing, to identify disease-causing mutations associated with congenital disorders of glycosylation. They discuss cost effective development and validation of a sequencing panel to test 24 genes that resulted in identification of positive controls and a number of variants.
Two further research papers by different groups at Stanford University focus upon ground breaking advances using Fluidigm IFC technology in single-cell gene expression.
The first article details how a team of researchers from Stanford School of Medicine has discovered how to induce non-neuronal cells into becoming functional neurons with classic neuronal morphologies, protein markers, gene expression, and action potentials. Their data demonstrate that non-neuronal human somatic cells, as well as pluripotent stem cells, can be converted directly into neurons by insertion of neuronal transcription factors. These methods may facilitate robust generation of person-specific human neurons for in vitro disease modeling or future applications in regenerative medicine.
The second article details how researchers at Stanford University have studied the transcription factors and signalling pathways that aid the formation of neurons. They discovered that miR-9/9 and miR-124 are involved in the induction of neuronal morphology. Using single-cell gene expression, they were able to characterize neurons in these mRNAs and further study their role in human neurogenesis.
The Fall 2011 newsletter also provides details of a free seminar entitled 'Learn how your targeted resequencing can be as easy as 1-2-3' to be held at the forthcoming ASHG / ICHG conference in Montreal. Links are provided to events around the world that Fluidigm will be attending in the latter months of 2011.
The Fall 2011 edition of the Fluidigm Corporation Community Newsletter is now available free to download from www.fluidigm.com/home/fluidigm/email/Q3_2011.html
This blog has been set up for editors, reviewers, authors and readers of Elsevier's Analytical Chemistry Journals - all of which can be seen below. It will be updated from Monday to Friday with general news and announcements concerning the titles listed on this page. It should be noted that the views or claims made in the news items and feeds are not necessarily those of the Publisher.
World Congress on Biosensors 2014
Biosensors 2014
Wednesday, 16 November 2011
Tuesday, 15 November 2011
Just Published: Sensors & Actuators B: Chemical
A new issue of this journal has just been published. To see abstracts of the papers it contains (with links through to the full papers) click here:
Selected papers from the latest issue:
Fabrication of stable low voltage organic bistable memory device
13 November 2011, 00:07:42
Publication year: 2011
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Ch.V.V. Ramana, M.K. Moodely, V. Kannan, A. Maity, J. Jayaramudu, ...
Organic bistable memory device was fabricated by spin coating of polymethyl methacrylate (PMMA): ZnO nanoparticles onto ITO coated glass. The thin films were characterized by Raman, SEM, AFM and FTIR spectroscopies. The electrical characterization showed that the two-terminal device exhibited excellent switching characteristics with ON/OFF ratio greater than 2 × 10when the voltage was swept between -2 V and +2 V. The device maintained its state even after removal of the bias voltage. Device did not show degradation after 1-h retention test at 120 °C. The memory functionality was consistent even after multiple cycles of operation and the device is reproducible. The switching mechanism is discussed on the basis of carrier transport mechanism. This demonstration provides a class of memory devices with the potential for extremely low-cost, low-power consumption applications, such as digital memory cell.
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Ch.V.V. Ramana, M.K. Moodely, V. Kannan, A. Maity, J. Jayaramudu, ...
Organic bistable memory device was fabricated by spin coating of polymethyl methacrylate (PMMA): ZnO nanoparticles onto ITO coated glass. The thin films were characterized by Raman, SEM, AFM and FTIR spectroscopies. The electrical characterization showed that the two-terminal device exhibited excellent switching characteristics with ON/OFF ratio greater than 2 × 10when the voltage was swept between -2 V and +2 V. The device maintained its state even after removal of the bias voltage. Device did not show degradation after 1-h retention test at 120 °C. The memory functionality was consistent even after multiple cycles of operation and the device is reproducible. The switching mechanism is discussed on the basis of carrier transport mechanism. This demonstration provides a class of memory devices with the potential for extremely low-cost, low-power consumption applications, such as digital memory cell.
Highly Selective Amperometric Sensors for Carbon Monoxide Detection in Exhaust Gas
13 November 2011, 00:07:42
Publication year: 2011
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Chanadda Phawachalotorn, Oravan Sanguanruang, Tatsumi Ishihara
An amperometric electrochemical sensor based on LaGaO3was demonstrated as highly sensitive to carbon monoxide (CO) in the temperatures ranging from 300 °C to 500 °C. In the present study, various Fe-doped LaGaO3electrolytes (La0.8Sr0.2Ga0.8Mg0.2-xFexO3; x = 0.05, 0.10, 0.15, 0.2 and La0.8Sr0.2Ga1-xFexO3; x = 0.10, 0.15, 0.2, 0.3) coupled with Au10wt%-In1.9Sn0.1O3(ITO955) and RuO2-La0.6Sr0.4CoO3(LSC64) as the electrode catalysts were investigated. Highest sensitivity was achieved at 8.83 mA(decade (at 500 °C) by doping 15 mol% Fe into electrolyte (denoted as LSGF 828515) among the examined electrolytes. The sensitivities of all studied sensors were high and the current increased with increasing CO concentration. The sensors were fast, highly sensitive to CO and almost insensitive to other coexisting gases such as CH4, CO2, and H2. Therefore, this sensor can be used for CO monitoring of exhaust gas from a small indoor combustion source.
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Chanadda Phawachalotorn, Oravan Sanguanruang, Tatsumi Ishihara
An amperometric electrochemical sensor based on LaGaO3was demonstrated as highly sensitive to carbon monoxide (CO) in the temperatures ranging from 300 °C to 500 °C. In the present study, various Fe-doped LaGaO3electrolytes (La0.8Sr0.2Ga0.8Mg0.2-xFexO3; x = 0.05, 0.10, 0.15, 0.2 and La0.8Sr0.2Ga1-xFexO3; x = 0.10, 0.15, 0.2, 0.3) coupled with Au10wt%-In1.9Sn0.1O3(ITO955) and RuO2-La0.6Sr0.4CoO3(LSC64) as the electrode catalysts were investigated. Highest sensitivity was achieved at 8.83 mA(decade (at 500 °C) by doping 15 mol% Fe into electrolyte (denoted as LSGF 828515) among the examined electrolytes. The sensitivities of all studied sensors were high and the current increased with increasing CO concentration. The sensors were fast, highly sensitive to CO and almost insensitive to other coexisting gases such as CH4, CO2, and H2. Therefore, this sensor can be used for CO monitoring of exhaust gas from a small indoor combustion source.
Detection of bisphenol A using an opal photonic crystal sensor
13 November 2011, 00:07:42
Publication year: 2011
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Chun Guo, Caihong Zhou, Na Sai, BaoAn Ning, Ming Liu, ...
A new opal photonic crystal sensor (OPCS) that allows the detection of label-free bisphenol A (BPA) is proposed in the current study. The concept of developing photonic-based sensors using combined photonic crystal technology and molecular imprinting techniques is introduced. First batches of the BPA-imprinted monodisperse PMMA spheres with a diameter of 220( ( 5)nm were prepared based on the suspension polymerization, so numerous nanocavities derived from BPA imprinting were distributed in the PMMA spheres. The liquid monodisperse microspheres were made into a polymerized crystalline colloidal array (PCCA) opal photonic crystal sensor. The inherent high affinity of the nanocavities distributed in the sphere allows OPCS to recognize BPA specifically. The sensor is characterized by a 3D-ordered interconnected lattice structure. Between the monospheres, there are well-arranged pores allowing the target molecules to embed and transport. As a result, changes in diffraction intensity which are related to BPA concentrations can be observed with the sensor. The detection ranges of OPCS are at 1 ng/ml–1 μg/ml level. The new sensory system has high selectivity of the target molecules in their natural forms, is easy to use, and costs low. Overall, the proposed approach provides a versatile analytical system for the establishment of a new sensor for the detection of endocrine-disrupting chemicals.
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Chun Guo, Caihong Zhou, Na Sai, BaoAn Ning, Ming Liu, ...
A new opal photonic crystal sensor (OPCS) that allows the detection of label-free bisphenol A (BPA) is proposed in the current study. The concept of developing photonic-based sensors using combined photonic crystal technology and molecular imprinting techniques is introduced. First batches of the BPA-imprinted monodisperse PMMA spheres with a diameter of 220( ( 5)nm were prepared based on the suspension polymerization, so numerous nanocavities derived from BPA imprinting were distributed in the PMMA spheres. The liquid monodisperse microspheres were made into a polymerized crystalline colloidal array (PCCA) opal photonic crystal sensor. The inherent high affinity of the nanocavities distributed in the sphere allows OPCS to recognize BPA specifically. The sensor is characterized by a 3D-ordered interconnected lattice structure. Between the monospheres, there are well-arranged pores allowing the target molecules to embed and transport. As a result, changes in diffraction intensity which are related to BPA concentrations can be observed with the sensor. The detection ranges of OPCS are at 1 ng/ml–1 μg/ml level. The new sensory system has high selectivity of the target molecules in their natural forms, is easy to use, and costs low. Overall, the proposed approach provides a versatile analytical system for the establishment of a new sensor for the detection of endocrine-disrupting chemicals.
Gold Nanoparticles-Modified Screen-Printed Carbon Electrodes For Anodic Stripping Voltammetric Determination Of Mercury In Ambient Water Samples
13 November 2011, 00:07:42
Publication year: 2011
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
E. Bernalte, C. Marín Sánchez, E. Pinilla Gil
We present here a simple, fast and cheap procedure for the determination of Hg(II) by square wave anodic stripping voltammetry (SWASV) at a commercial gold nanoparticles-modified screen-printed carbon electrodes (AuNPs-SPCEs), as a tool for environmental waters monitoring. The advantages of electrode nanostructuration are exploited, e.g. no stirring for the deposition step is needed. The surface of the gold nanostructured screen-printed carbon electrodes were characterized using SEM, XPS and electrochemical methods. All experimental variables involved in the voltammetric stripping method were optimized to develop a reliable method capable of measuring dissolved mercury in the low ng/mL range. The proposed method was tested with the NIST 1641d Mercury in Water Standard Reference Material with good agreement. The applicability of the AuNPs-SPCEs for Hg(II) determination in real ambient water samples, namely rain water, river water and industrial waste water, without any sample pretreatment, was successfully demonstrated.
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
E. Bernalte, C. Marín Sánchez, E. Pinilla Gil
We present here a simple, fast and cheap procedure for the determination of Hg(II) by square wave anodic stripping voltammetry (SWASV) at a commercial gold nanoparticles-modified screen-printed carbon electrodes (AuNPs-SPCEs), as a tool for environmental waters monitoring. The advantages of electrode nanostructuration are exploited, e.g. no stirring for the deposition step is needed. The surface of the gold nanostructured screen-printed carbon electrodes were characterized using SEM, XPS and electrochemical methods. All experimental variables involved in the voltammetric stripping method were optimized to develop a reliable method capable of measuring dissolved mercury in the low ng/mL range. The proposed method was tested with the NIST 1641d Mercury in Water Standard Reference Material with good agreement. The applicability of the AuNPs-SPCEs for Hg(II) determination in real ambient water samples, namely rain water, river water and industrial waste water, without any sample pretreatment, was successfully demonstrated.
Simultaneous OWLS and EIS monitoring of supported lipid bilayers with the pore forming peptide melittin
13 November 2011, 00:07:42
Publication year: 2011
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Kaori Sugihara, Marco Delai, Istvan Szendro, Orane Guillaume-Genti, János Vörös, ...
A simultaneous optical waveguide lightmode spectroscopy (OWLS) and electrochemical impedance spectroscopy (EIS) measurement was carried out for the investigation of a supported lipid bilayer and its interactions with a pore-forming peptide, melittin. It was achieved only after the optimization of the ITO coating on the waveguide to increase the electrical sensitivity and the functionalization of the waveguide with a polyelectrolyte to form a lipid bilayer over the ITO surface. The combined system enabled monitoring of melittin pore activities in a wider range of melittin concentrations than either technique alone (1 μg/ml <Cmelittin < 200 μg/ml). Furthermore, it provided unique information that could not be obtained by the individual methods, such as a better identification of the melittin-pore formation and an insight about the correlation between the total pore area vs adsorbed amount of melittin.
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Kaori Sugihara, Marco Delai, Istvan Szendro, Orane Guillaume-Genti, János Vörös, ...
A simultaneous optical waveguide lightmode spectroscopy (OWLS) and electrochemical impedance spectroscopy (EIS) measurement was carried out for the investigation of a supported lipid bilayer and its interactions with a pore-forming peptide, melittin. It was achieved only after the optimization of the ITO coating on the waveguide to increase the electrical sensitivity and the functionalization of the waveguide with a polyelectrolyte to form a lipid bilayer over the ITO surface. The combined system enabled monitoring of melittin pore activities in a wider range of melittin concentrations than either technique alone (1 μg/ml <Cmelittin < 200 μg/ml). Furthermore, it provided unique information that could not be obtained by the individual methods, such as a better identification of the melittin-pore formation and an insight about the correlation between the total pore area vs adsorbed amount of melittin.
Detection of Low Molecular Weight Compounds using Carbon Nanotube Grafted Resonators
13 November 2011, 00:07:42
Publication year: 2011
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Al. Palaniappan, W.H. Goh, U.H. Yildiz, B. Swarnalatha, S. Priyanka, ...
A biosensor platform based on single walled carbon nanotube (SWCNT) grafted quartz resonator is reported in this study. The generated SWCNT network on the resonator electrode is used to enhance the surface area for receptor immobilization and thereby the sensitivity. This approach enables detection of low molecular weight compounds in a direct assay format. Micro-gravimetric detection of two potentially harmful herbicides, atrazine and 2,4-dichlorophenoxyacetic acid (2,4-D) demonstrates the enhanced sensing capabilities of the developed biosensor platform. Antibodies raised against the herbicides are covalently attached to the SWCNTs, which are tethered on to the resonator electrodes via cysteine linkers. Imaging surface plasmon resonance and polarization modulation infrared reflection absorption spectroscopy are used to characterize the sensing surface and the covalent immobilization of the antibodies. The experimental results reveal that grafting SWCNT on resonator electrodes improve the sensing performance, as compared to a planar architecture, thereby enabling direct detection of atrazine and 2,4-D at analytically relevant concentration levels.
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
Al. Palaniappan, W.H. Goh, U.H. Yildiz, B. Swarnalatha, S. Priyanka, ...
A biosensor platform based on single walled carbon nanotube (SWCNT) grafted quartz resonator is reported in this study. The generated SWCNT network on the resonator electrode is used to enhance the surface area for receptor immobilization and thereby the sensitivity. This approach enables detection of low molecular weight compounds in a direct assay format. Micro-gravimetric detection of two potentially harmful herbicides, atrazine and 2,4-dichlorophenoxyacetic acid (2,4-D) demonstrates the enhanced sensing capabilities of the developed biosensor platform. Antibodies raised against the herbicides are covalently attached to the SWCNTs, which are tethered on to the resonator electrodes via cysteine linkers. Imaging surface plasmon resonance and polarization modulation infrared reflection absorption spectroscopy are used to characterize the sensing surface and the covalent immobilization of the antibodies. The experimental results reveal that grafting SWCNT on resonator electrodes improve the sensing performance, as compared to a planar architecture, thereby enabling direct detection of atrazine and 2,4-D at analytically relevant concentration levels.
CO optical sensing properties of nanocrystalline ZnO-Au films: effect of doping with transition metal ions
13 November 2011, 00:07:42
Publication year: 2011
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
E. Della Gaspera, M. Guglielmi, G. Perotto, S. Agnoli, G. Granozzi, ...
Zinc oxide nanocrystals, pure and doped with transition metal ions, have been synthesized using colloidal techniques; after purification and concentration protocols, the ZnO solutions are mixed with monodisperse Au colloidal suspensions and used for thin film depositions. The effect of the dopant ions on the structural, morphological and optical properties of the as-synthesized colloids as well as the nanocomposite thin films has been analyzed and discussed. The dopant presence has been found to affect the CO optical sensing properties of the nanocomposite ZnO-Au films: compared to pure ZnO, an increase in sensitivity up to 80% and 55% has been detected for Co-doped and Mn-doped ZnO respectively, while Ni-doped ZnO films show only minor improvements. This observation has been ascribed to the multiple oxidation states of cobalt and manganese ions that can facilitate electron transfer between the target gas and the semiconductive oxide matrix, and also to the lower surface concentration of Ni ions inside ZnO crystals, as compared to Co and Mn. A fast and reversible response after repeated CO exposures has been detected for all tested samples, and a linear response intensity with the order of magnitude of CO concentration has been observed in the 10-10000 ppm range, with a lower detection limit of 1-2 ppm.
Source: Sensors and Actuators B: Chemical, Available online 12 November 2011
E. Della Gaspera, M. Guglielmi, G. Perotto, S. Agnoli, G. Granozzi, ...
Zinc oxide nanocrystals, pure and doped with transition metal ions, have been synthesized using colloidal techniques; after purification and concentration protocols, the ZnO solutions are mixed with monodisperse Au colloidal suspensions and used for thin film depositions. The effect of the dopant ions on the structural, morphological and optical properties of the as-synthesized colloids as well as the nanocomposite thin films has been analyzed and discussed. The dopant presence has been found to affect the CO optical sensing properties of the nanocomposite ZnO-Au films: compared to pure ZnO, an increase in sensitivity up to 80% and 55% has been detected for Co-doped and Mn-doped ZnO respectively, while Ni-doped ZnO films show only minor improvements. This observation has been ascribed to the multiple oxidation states of cobalt and manganese ions that can facilitate electron transfer between the target gas and the semiconductive oxide matrix, and also to the lower surface concentration of Ni ions inside ZnO crystals, as compared to Co and Mn. A fast and reversible response after repeated CO exposures has been detected for all tested samples, and a linear response intensity with the order of magnitude of CO concentration has been observed in the 10-10000 ppm range, with a lower detection limit of 1-2 ppm.
Freeze Drying of Pharmaceuticals & Biologicals
SP Scientific has announced new dates for its popular educational seminars and hands-on laboratory training courses in freeze drying techniques.
A new seminar 'Freeze Drying of Pharmaceuticals & Biologicals' has been developed in conjunction with Dr. Henning Gieseler and the University of Erlangen Freeze Drying Focus Group - one of the premier academic groups in the world focused on lyophilization. This series of one day seminars** (Nov 14th, Nov 17th & Nov 18th 2011) will provide the novice with a basic freeze drying overview and the expert with up-to-date information on topics of interest to the lyophilization scientist operating in a pharmaceutical or biological environment. Scheduled question and answer sessions will provide attendees with the opportunity to have their own specific questions and concerns addressed.
In response to the overwhelming demand for the 'Lyophilization Cycle Development & Optimization: A Laboratory Based Approach' hands-on training course delivered by Dr Jeff Schwegman, a new session has been added for December 6-8th 2011. This course will focus on following the freeze drying process from formulation and thermal analysis to cycle development and optimization, packaging and troubleshooting. Attendees at the training course will have the chance to optimize their learning experience by using tangible applications in a controlled setting. SP Scientific's 3-day training courses have been designed to enable people involved with lyophilisation, at all levels of experience, to gain considerable benefit and network with fellow professionals.
For further information, or to reserve space for the educational seminars or hands-on training course please contact SP Scientific on +1-845-255-5000 x2311 / shireen.scott@spscientific.com.
SP Scientific is a leading manufacturer of laboratory to production scale freeze dryers / lyophilizers, centrifugal evaporators and concentrators, thermal control system and glassware washers. The company sells its products under well-known brands including FTS™, VirTis®, Genevac® and Hotpack®. SP Scientific has ISO 9001:2008 registered production facilities in the USA and Europe.
A new seminar 'Freeze Drying of Pharmaceuticals & Biologicals' has been developed in conjunction with Dr. Henning Gieseler and the University of Erlangen Freeze Drying Focus Group - one of the premier academic groups in the world focused on lyophilization. This series of one day seminars** (Nov 14th, Nov 17th & Nov 18th 2011) will provide the novice with a basic freeze drying overview and the expert with up-to-date information on topics of interest to the lyophilization scientist operating in a pharmaceutical or biological environment. Scheduled question and answer sessions will provide attendees with the opportunity to have their own specific questions and concerns addressed.
In response to the overwhelming demand for the 'Lyophilization Cycle Development & Optimization: A Laboratory Based Approach' hands-on training course delivered by Dr Jeff Schwegman, a new session has been added for December 6-8th 2011. This course will focus on following the freeze drying process from formulation and thermal analysis to cycle development and optimization, packaging and troubleshooting. Attendees at the training course will have the chance to optimize their learning experience by using tangible applications in a controlled setting. SP Scientific's 3-day training courses have been designed to enable people involved with lyophilisation, at all levels of experience, to gain considerable benefit and network with fellow professionals.
For further information, or to reserve space for the educational seminars or hands-on training course please contact SP Scientific on +1-845-255-5000 x2311 / shireen.scott@spscientific.com.
SP Scientific is a leading manufacturer of laboratory to production scale freeze dryers / lyophilizers, centrifugal evaporators and concentrators, thermal control system and glassware washers. The company sells its products under well-known brands including FTS™, VirTis®, Genevac® and Hotpack®. SP Scientific has ISO 9001:2008 registered production facilities in the USA and Europe.
Monday, 14 November 2011
Milk and Milk Powder Rapid Testing
ELISA screening kits from Randox Food Diagnostics are now available for the rapid detection for a range of antimicrobial and growth promoting compounds in both milk and milk powder. The extensive range of testing includes beta agonists (clenbuterol and salbutamol), ractopamine, quinolones, beta lactams, sulphonamides and chloramphenicol.
A simple one step sample preparation allows labour to be considerably reduced; a simple centrifugation of samples is all that is required before application to multiple ELISA kits. Productivity can be maximised in any milk testing environment with results for up to 40 samples being available in less than 90mins.
Benefits Include:-
- Simple sample preparations
- Low limits of detections
- Easy to use
Please visit our website for more information: http://www.randoxfooddiagnostics.com/ or email enquiries@randoxfooddiagnostics.com
Company Profile:
Randox Food Diagnostics is a division of Randox Laboratories who have 30 years experience in the diagnostic market and a devoted research and development team. We provide a range of excellent tools for screening for antimicrobials, growth promoting hormones and drugs of abuse in animals and foodstuffs, as well as our dedicated testing kits for the wine and beverage markets. Randox Food Diagnostics offer excellent limit of detections and simple sample preparations. Our portfolio includes 27 ELISA’s and 7 multiplex screening platforms. All products are manufactured at our state-of-the-art ISO 13485 accredited manufacturing plant in the UK
Friday, 11 November 2011
NEW Capnograph for Small Rodents & Respiratory Mechanics
Harvard Apparatus-Hugo Sachs Electronik is proud to introduce the Type 340 Capnograph for small rodents. This extremely low dead space Capnograph makes it suitable for mice as well as other small rodents. This Capnograph is easily expanded, by adding low dead space flow heads for basic respiratory mechanics.
Holliston, Massachusetts 01746 USA
Toll Free: 800-272-2775
Phone: 508-893-8999
Fax: 508-429-5732
E-mail: bioscience@harvardapparatus.com
Web: http://www.harvardapparatus.com/
The Harvard Apparatus–Hugo Sachs Electronik Capnograph is a low volume system that provides continuous measurement of end-tidal CO2 through a highly sensitive infrared spectroscopy sensor. This NEW Capnograph has the greatest operational range on the market, and is sensitive enough to be suitable for breathing ranges from 0-300 bpm. Data is displayed in real time; and with the analog ports, data can be collected simultaneously with most commercial data acquisition systems.
The basic Capnograph displays respiration rate in freely breathing or ventilated animals, as well as end tidal CO2 for every breath. This provides is the best information about the health of the animal and effectiveness of the anestheia level.
If the basic capnographic functions are not enough, then the optional flow heads expand the Capnograph to measure Peak Inspiratory and Expiratory Flow, Peak Inspiratory Pressure, Positive End Expiratory Pressure, and Tidal Volume. This is valuable information about the health of the lungs during the experiment, and any changes to the physiological state. The user can also use the flow heads to calibrate between several surgical set-ups, ensuring that every experiment is conducted the same between every animal, and every ventilator.
For more information about the Harvard Apparatus-Hugo Sachs Electronik Capnograph, anesthesia products, or any of their ventilators, please contact your local representative or our technical support department.
Harvard Apparatus84 October Hill RoadHolliston, Massachusetts 01746 USA
Toll Free: 800-272-2775
Phone: 508-893-8999
Fax: 508-429-5732
E-mail: bioscience@harvardapparatus.com
Web: http://www.harvardapparatus.com/
AirClean Systems polypropylene sliding-sash ductless fume hoods are now available in 36” deep models.
AirClean Systems’ ductless fume hood lineup has been further expanded to provide lab designers with a generous range of options without the need for costly customization. Based on AirClean Systems’ proven 30” depth design, the new 36” depth is available in AirClean Systems 3-, 4-, 6- and 8-foot wide folding-sash ductless fume hood models.
These 30” and 36” deep polypropylene ductless fume hoods utilize a unique gas phase bonded carbon filter. This filter, found only in AirClean Systems safety products, eliminates filter dusting and dead zones associated with traditional granular carbon filters. Each unit features a microprocessor-based automatic safety controller, keeping constant check on airflow and filter quality, and alerting the operator in the event of filter saturation.
AirClean Systems’ ductless fume hoods feature many of the features found on traditional total exhaust hoods, namely dual-wall construction for plumbing and mounting fixtures, and vertical sliding safety glass sash. However, the seamless polypropylene construction is chemically resistant and will not rust.
All hoods are designed to house up to 7 inches of filtration. By stacking a HEPA filter, followed by a bonded carbon filter, the operator can effectively remove both toxic particulate and chemical fumes. For high evaporation or multiple chemical applications, a full 7 inch stack of carbon filtration may be recommended.
AirClean Systems ductless fume hoods meet and exceed relevant OSHA and ANSI Z9.5 standards.
Find more product information at http://www.aircleansystems.com/OP_PHoods.htm
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