Until now, you couldn't get around having two systems if you wanted to use analytical and then preparative HPLC - not to mention the high costs and problem of space.
KNAUER now reveals that there is also an easier way. Using just one high pressure gradient unit, the new Smartline ScaleUp System can analytically separate and purify products in a gram scale. In this way, the user accomplishes the same goal as with two HPLC systems. 
This is achieved by preliminary optimization of the method under analytical conditions followed by preparative separation and fractionation of the sample using the same unit.
Future-proof: An advantage compared to other available solutions is that KNAUER can respond directly to the customers' requirements due to the modular system design, i.e. select the components that are actually needed for the applications. Modifications or additions are easy to do.
No compromises: There are two separate flow paths - one for the analytical and one for the preparative application. This results in a very low dead volume that is especially important for the analytical stage. The system also makes no compromises during detection as it uses two separate detectors - one with a photodiode array and another with a variable wavelength where the volume and path length of the flow cells are optimally adapted to the relevant application area.
Adaptable: The preparative stage is suitable for flow rates up to 100 ml/min and 200 ml/min, i.e. the user can choose whether he wants a 100 ml or a 200 ml pump head. This increases the range of applications. The 100 ml pump head is preferable when using separation columns with small particles because it can reach a pressure of 400 bar. Less back pressure is produced when working with larger particles (e.g. 10 µm). The user benefits from the larger flow range with the 200 ml head.
Full integration with KNAUER's GLP conform ChromGate® chromatography data software makes the Smartline ScaleUp system easy to control and provides a complete set of analytical functions as well as advanced fraction collection capabilities.
)
The new ScaleUp System from KNAUER is the perfect tool for the development of preparative applications.
No comments:
Post a Comment