Recently published research performed at the National Institute of Standards and Technology (NIST) may breathe new life into the use of a powerful, if tricky, diagnostic technique for cell biology. The paper, which is to be presented in the Biophysical Journal, demonstrates that with improved hardware and better signal processing, a powerful form of molecular vibration spectroscopy can quickly deliver detailed molecular maps of the contents of cells without damaging them. Earlier studies have suggested that, to be useful, the technique would need power levels too high to maintain cell integrity.
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