Introduction: Automated in-liner thermochemolysis-gas chromatography-mass spectrometry (THM-GC-MS) is a promising approach for fast diagnosing of tuberculosis in an early state. Sputum or bacterial cultures can be injected with a minimum of sample preparation and the detection limits are comparable with those of microscopic tests. Unfortunately, the known biomarkers, for example tuberculostearic acid, are not fully specific for tuberculosis.
In this study, the presences of new potential biomarkers was investigated . This with the aim to reduce the risk of false positives. To find novel markers, a set of cultured bacteria samples were measured followed by chemometric evaluation of the THM-GC.
See the full paper at: www.atasgl.com/nl/download/Poster-TB-HET.pdf
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