GenePORTER® Gold from AMSBIO is a new highly efficient and reproducible lipid-based reagent for effective transfection of a wide variety of cell lines.
Molecular target delivery faces many barriers, from crossing the cell type-specific extracellular membrane, to cytoplasmic degradation and translocation across the nuclear membrane. To be effective, the transfection reagent/DNA complexes must overcome all of these challenges whilst minimizing cytotoxicity.
Traditionally the most efficient delivery methods have also been the most cytotoxic. Using Advanced Carrier Enhancement technology, a nuclear targeting mechanism that maximizes transfection and transgene expression levels while still maintaining high cell viability, GenePORTER® Gold has been able to address this limitation.
Based on generations of proven cationic lipid formulations with more than 850 citations to date, GenePORTER® Gold uniquely combines consistent delivery and reliability with the lowest reported cytotoxicity of commercially available transfection reagents. The GenePORTER® Gold protocol has been optimized to provide simple, same-day transfection making it ideal for high throughput or large scale applications where the need for consistent results is highly desirable.
For further information on GenePORTER® Gold Transfection Reagent please visit http://www.amsbio.com/GenePORTER-Gold-Transfection-Reagent.aspx or contact AMSBIO on +44-1235-828200 / email info@amsbio.com.
Founded in 1987, AMS Biotechnology (AMSBIO) is recognized as a leading international provider of unique & innovative products & custom services for life sciences research. The amsbio range includes over 23,000 polyclonal & monoclonal antibodies, peptides, recombinant proteins, extracellular matrix, molecular detection reagents, & tissue DNA, RNA, protein & microarray products. Key research areas include: apoptosis, cell invasion & migration, cell signaling, DNA damage, electrophoresis, glycobiology, posttranslational modification & stem cell biology.
Molecular target delivery faces many barriers, from crossing the cell type-specific extracellular membrane, to cytoplasmic degradation and translocation across the nuclear membrane. To be effective, the transfection reagent/DNA complexes must overcome all of these challenges whilst minimizing cytotoxicity.
Traditionally the most efficient delivery methods have also been the most cytotoxic. Using Advanced Carrier Enhancement technology, a nuclear targeting mechanism that maximizes transfection and transgene expression levels while still maintaining high cell viability, GenePORTER® Gold has been able to address this limitation.
Based on generations of proven cationic lipid formulations with more than 850 citations to date, GenePORTER® Gold uniquely combines consistent delivery and reliability with the lowest reported cytotoxicity of commercially available transfection reagents. The GenePORTER® Gold protocol has been optimized to provide simple, same-day transfection making it ideal for high throughput or large scale applications where the need for consistent results is highly desirable.
For further information on GenePORTER® Gold Transfection Reagent please visit http://www.amsbio.com/GenePORTER-Gold-Transfection-Reagent.aspx or contact AMSBIO on +44-1235-828200 / email info@amsbio.com.
Founded in 1987, AMS Biotechnology (AMSBIO) is recognized as a leading international provider of unique & innovative products & custom services for life sciences research. The amsbio range includes over 23,000 polyclonal & monoclonal antibodies, peptides, recombinant proteins, extracellular matrix, molecular detection reagents, & tissue DNA, RNA, protein & microarray products. Key research areas include: apoptosis, cell invasion & migration, cell signaling, DNA damage, electrophoresis, glycobiology, posttranslational modification & stem cell biology.
Transfection can be more efficient. This video describes how this can be accomplished. http://www.americanbiotechnologist.com/blog/primary-cell-transfection/
ReplyDelete