The Spring 2011 edition of the Fluidigm Corporation Community Newsletter is now available to download from www.fluidigm.com/home/fluidigm/email/2011_Q1_Newsletter.html.
The Fluidigm Community Newsletter is a quarterly publication dedicated to providing you with the most recent research, product updates, and news featuring Fluidigm integrated fluidic circuit (IFC) technology. Each issue is dedicated to providing new information of interest including new products, applications and customer advances to researchers involved with gene expression, SNP genotyping and sample preparation for next generation sequencing.
In the Spring 2011 issue, researchers from the Institute for Stem Cell Biology and Regenerative Medicine, School of Medicine at Stanford University, USA, report upon how induced human pluripotent stem cells can differentiate into primordial germ cells under specific culture conditions. Using quantitative real-time PCR carried out with Fluidigm 48.48 Dynamic Array™ IFCs on the BioMark™ System, increased expression of germ cell marker genes was found in the cells after differentiation. A major cause of infertility in humans is production of few or no germ cells, yet little is known about human germ cell development because the process occurs early in embryos. The culture system described in this article may provide a model to study human germ cell development.
Another paper presented in the newsletter from the University of California, San Francisco, describes a new microfluidic-based multiplex quantitative real-time PCR technique and how it was used to identify microRNA signatures in sera of prostate cancer patients. The paper details a high-throughput, multiplex, quantitative real-time PCR method, using Fluidigm 96.96 Dynamic Array IFCs and the BioMark System, and how it was used to quantify miRNAs in sera from 48 patients. In the study several miRNAs were identified that correlate with presence and severity of disease.
Complimenting the independent customer research publications, the Spring 2011 newsletter also provides an introduction to Fluidigm's new advanced genomic analysis system, the BioMark HD, as well as providing access to a comprehensive bibliography of single-cell research publications.
This blog has been set up for editors, reviewers, authors and readers of Elsevier's Analytical Chemistry Journals - all of which can be seen below. It will be updated from Monday to Friday with general news and announcements concerning the titles listed on this page. It should be noted that the views or claims made in the news items and feeds are not necessarily those of the Publisher.
Thanks to share latest advances using IFC technology. Nice work keep it up !!!
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