A new issue of this journal has just been published. To see abstracts of the papers it contains (with links through to the full papers) click here:
Selected papers from the latest issue:Femtomolar DNA detection by parallel colorimetric darkfield microscopy of functionalized gold nanoparticles
23 June 2011, 22:23:56
Publication year: 2011
Source: Biosensors and Bioelectronics, In Press, Accepted Manuscript, Available online 23 June 2011
Remco, Verdoold , Ron, Gill , Felicia, Ungureanu , Robert, Molenaar , Rob P.H., Kooyman
We introduce a sensing platform for specific detection of DNA based on the formation of gold nanoparticles dimers on a surface. The specific coupling of a second gold nanoparticle to a surface bound nanoparticle by DNA hybridization results in a red shift of the nanoparticle plasmon peak. This shift can be detected as a color change in the darkfield image of the gold nanoparticles. Parallel detection of hundreds of gold nanoparticles with a calibrated true color camera enabled us to detect specific binding of target DNA. This enables a limit of detection below 1.0×10−14M without the need for a spectrometer...
Source: Biosensors and Bioelectronics, In Press, Accepted Manuscript, Available online 23 June 2011
Remco, Verdoold , Ron, Gill , Felicia, Ungureanu , Robert, Molenaar , Rob P.H., Kooyman
We introduce a sensing platform for specific detection of DNA based on the formation of gold nanoparticles dimers on a surface. The specific coupling of a second gold nanoparticle to a surface bound nanoparticle by DNA hybridization results in a red shift of the nanoparticle plasmon peak. This shift can be detected as a color change in the darkfield image of the gold nanoparticles. Parallel detection of hundreds of gold nanoparticles with a calibrated true color camera enabled us to detect specific binding of target DNA. This enables a limit of detection below 1.0×10−14M without the need for a spectrometer...
Controlled immobilization of acetylcholinesterase on improved hydrophobic gold nanoparticle/prussian blue modified surface for ultra-trace organophosphate pesticide detection
23 June 2011, 22:23:56
Publication year: 2011
Source: Biosensors and Bioelectronics, In Press, Accepted Manuscript, Available online 23 June 2011
Shuo, Wu , Xiaoqin, Lan , Wei, Zhao , Yupeng, Li , Lihui, Zhang , ...
An ultrasensitive amperometric acetylcholinesterase (AChE) biosensor was fabricated by controlled immobilization of AChE on gold nanoparticles/poly(dimethyldiallylammonium chloride) protected Prussian blue (Au-PDDA-PB) nanocomposite modified electrode surface for the detection of organophorous pesticide. The Au-PDDA-PB membrane served as an excellent matrix for the immobilization of enzyme, which not only enhanced electron transfer but also possessed a relatively large surface area. In addition, the surface hydrophilicity of the Au-PDDA-PB nanocomposite was finely controlled in the static water contact angle range of 25.6 to 78.1° by adjusting the ratio of gold nanoparticles to PDDA-PB. On an optimized hydrophobic surface, the AChE adopts an orientation...
Source: Biosensors and Bioelectronics, In Press, Accepted Manuscript, Available online 23 June 2011
Shuo, Wu , Xiaoqin, Lan , Wei, Zhao , Yupeng, Li , Lihui, Zhang , ...
An ultrasensitive amperometric acetylcholinesterase (AChE) biosensor was fabricated by controlled immobilization of AChE on gold nanoparticles/poly(dimethyldiallylammonium chloride) protected Prussian blue (Au-PDDA-PB) nanocomposite modified electrode surface for the detection of organophorous pesticide. The Au-PDDA-PB membrane served as an excellent matrix for the immobilization of enzyme, which not only enhanced electron transfer but also possessed a relatively large surface area. In addition, the surface hydrophilicity of the Au-PDDA-PB nanocomposite was finely controlled in the static water contact angle range of 25.6 to 78.1° by adjusting the ratio of gold nanoparticles to PDDA-PB. On an optimized hydrophobic surface, the AChE adopts an orientation...
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