A new issue of this journal has just been published. To see abstracts of the papers it contains (with links through to the full papers) click here:
Includes the following apaper:
Flow immunosensing system utilizing antibodies immobilized on beads coated with poly-2-[3-(methacryloylamino)propylammonio]ethyl 3-aminopropyl phosphate
31 May 2011, 20:35:55
Publication year: 2011
Source: Sensors and Actuators A: Physical, In Press, Accepted Manuscript, Available online 30 May 2011
Y., Fuchiwaki , M., Yasuzawa
In order to increase the signal-to-noise ratio of immunosensors, a flow immunosensing system was fabricated containing poly-2-[3-(methacryloylamino)propylammonio]ethyl 3-aminopropyl phosphate (poly-3MAm3AP) at the antigen-antibody reacted interface. Poly-3MAm3AP is a polymer containing phosphorylcholine groups (which act to attract water) and amino groups (useful for the covalent attachment of receptors). Anti-luteinizing hormone (LH) antibody-immobilized beads coated with poly-3MAm3AP were prepared and packed into the reactor column of a flow immunosensing system. Nonspecific anti-hemoglobin antibodies were also used in order to estimate the level of nonspecific adsorption. The fabricated immunosensing system not only significantly reduced nonspecific adsorption, but also detected signal intensity with superior...
Source: Sensors and Actuators A: Physical, In Press, Accepted Manuscript, Available online 30 May 2011
Y., Fuchiwaki , M., Yasuzawa
In order to increase the signal-to-noise ratio of immunosensors, a flow immunosensing system was fabricated containing poly-2-[3-(methacryloylamino)propylammonio]ethyl 3-aminopropyl phosphate (poly-3MAm3AP) at the antigen-antibody reacted interface. Poly-3MAm3AP is a polymer containing phosphorylcholine groups (which act to attract water) and amino groups (useful for the covalent attachment of receptors). Anti-luteinizing hormone (LH) antibody-immobilized beads coated with poly-3MAm3AP were prepared and packed into the reactor column of a flow immunosensing system. Nonspecific anti-hemoglobin antibodies were also used in order to estimate the level of nonspecific adsorption. The fabricated immunosensing system not only significantly reduced nonspecific adsorption, but also detected signal intensity with superior...
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