A new issue of this journal has just been published. To see abstracts of the papers it contains (with links through to the full papers) click here:
Selected papers from the latest issue:A novel, ultra sensible biosensor built by layer-by-layer covalent attachment of a receptor for diagnosis of tumor growth
04 September 2011, 20:17:26
Publication year: 2011
Source: Analytica Chimica Acta, In Press, Accepted Manuscript, Available online 3 September 2011
Zihni Onur, Uygun , Mustafa Kemal, Sezgintürk
In the presented research, a novel, ultra sensitive biosensor for the impedimetric detection of vascular endothelial growth factor (VEGF) is introduced. The human vascular endothelial growth factor receptor 1 (VEGFR1, Flt-1) was used as a biorecognition element for the first time. The immobilization of VEGF-R1 on glassy carbon electrodes was carried out using layer-by-layer covalent attachment of VEGF-R1. The electrochemical properties of the layers constructed on the electrodes were characterized by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). The differences in electron transfer resistance (Ret) between the working solution and the biosensor surface, recorded by the redox probe K3[Fe(CN)6]/K4[Fe(CN)6],...
Source: Analytica Chimica Acta, In Press, Accepted Manuscript, Available online 3 September 2011
Zihni Onur, Uygun , Mustafa Kemal, Sezgintürk
In the presented research, a novel, ultra sensitive biosensor for the impedimetric detection of vascular endothelial growth factor (VEGF) is introduced. The human vascular endothelial growth factor receptor 1 (VEGFR1, Flt-1) was used as a biorecognition element for the first time. The immobilization of VEGF-R1 on glassy carbon electrodes was carried out using layer-by-layer covalent attachment of VEGF-R1. The electrochemical properties of the layers constructed on the electrodes were characterized by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). The differences in electron transfer resistance (Ret) between the working solution and the biosensor surface, recorded by the redox probe K3[Fe(CN)6]/K4[Fe(CN)6],...
Graphical abstract
Graphical abstract: Highlights: ► In the study entitled “A novel, ultra sensible biosensor built by layer-by-layer covalent attachment of VEGF Receptor-1(Flt-1): the analysis of vascular endothelial growth factor for diagnosis of tumor growth”, Vascular Entothelial Growth Factor Receptor-1 was used as a biorecegnition element as a first time in the literature. ► Moreover, as a measurement principle, EIS was used VEGF-R1/VEGF interaction as a first time again. ► A layer-by-layer immobilization procedure was original and enhanced the sensibility of the biosensor. ► Vascular endothelial Growth factor was detected in the range of 100-600 femtogram/mL which showed that the biosensor exhibited an ultra sensible for VEGF. ► In the manuscript, the impedance data were analyzed by the transform of Kramer-Kronigs.The development of an evaluation method for capture columns used in two-dimensional liquid chromatography
02 September 2011, 20:16:11
Publication year: 2011
Source: Analytica Chimica Acta, In Press, Accepted Manuscript, Available online 2 September 2011
Liwei, Cao , Danhua, Yu , Xinliang, Wang , Yanxiong, Ke , Yu, Jin , ...
Capture columns are important interface tools for on line two-dimensional liquid chromatography (2D-LC). In this study, a systematic method was developed to evaluate and optimize the capture ability of capture columns by off-line method. First, the parameter ΔtR (ΔtR = t2-t1-t0-W) was introduced to quantitatively represent the capture ability of the capture column by connecting a capture column behind the first dimensional column. Based on the value of ΔtR, an appropriate capture column was selected after the first dimensional column was fixed. Then, the capture ability of the selected column was promoted by adjusting the mobile phase of the first...
Source: Analytica Chimica Acta, In Press, Accepted Manuscript, Available online 2 September 2011
Liwei, Cao , Danhua, Yu , Xinliang, Wang , Yanxiong, Ke , Yu, Jin , ...
Capture columns are important interface tools for on line two-dimensional liquid chromatography (2D-LC). In this study, a systematic method was developed to evaluate and optimize the capture ability of capture columns by off-line method. First, the parameter ΔtR (ΔtR = t2-t1-t0-W) was introduced to quantitatively represent the capture ability of the capture column by connecting a capture column behind the first dimensional column. Based on the value of ΔtR, an appropriate capture column was selected after the first dimensional column was fixed. Then, the capture ability of the selected column was promoted by adjusting the mobile phase of the first...
Streptavidin-functionalized capillary immune microreactor for highly efficient chemiluminescent immunoassay
02 September 2011, 20:16:11
Publication year: 2011
Source: Analytica Chimica Acta, In Press, Accepted Manuscript, Available online 2 September 2011
Zhanjun, Yang , Chen, Zong , Huangxian, Ju , Feng, Yan
A streptavidin functionalized capillary immune microreactor was designed for highly efficient flow-through chemiluminescent (CL) immunoassay. The functionalized capillary could be used as both a support for highly efficient immobilization of antibody and a flow cell for flow-through immunoassay. The functionalized inner wall and the capture process were characterized using scanning electron microscopy. Compared to conventional packed tube or thin-layer cell immunoreactor, the proposed microreactor showed remarkable properties such as lower cost, simpler fabrication, better practicality and wider dynamic range for fast CL immunoassay with good reproducibility and stability. Using α-fetoprotein as model analyte, the highly efficient CL flow-through immunoassay system...
Source: Analytica Chimica Acta, In Press, Accepted Manuscript, Available online 2 September 2011
Zhanjun, Yang , Chen, Zong , Huangxian, Ju , Feng, Yan
A streptavidin functionalized capillary immune microreactor was designed for highly efficient flow-through chemiluminescent (CL) immunoassay. The functionalized capillary could be used as both a support for highly efficient immobilization of antibody and a flow cell for flow-through immunoassay. The functionalized inner wall and the capture process were characterized using scanning electron microscopy. Compared to conventional packed tube or thin-layer cell immunoreactor, the proposed microreactor showed remarkable properties such as lower cost, simpler fabrication, better practicality and wider dynamic range for fast CL immunoassay with good reproducibility and stability. Using α-fetoprotein as model analyte, the highly efficient CL flow-through immunoassay system...
No comments:
Post a Comment