Just Published: Analytica Chimica Acta

A new issue of this journal has just been published. To see abstracts of the papers it contains (with links through to the full papers) click here:

Analytica Chimica Acta
http://rss.sciencedirect.com/publication/science/5216

Selected papers from the latest issue:

Review articles

2.

Quality assessment and authentication of virgin olive oil by NMR spectroscopy: A critical review   Review Article Pages 1-27 Photis Dais, Emmanuel Hatzakis Graphical abstract Highlights ► Overview of olive oil analysis by1H,13C, and31P NMR spectroscopy. ► Sample preparation. ► Experimental conditions and processing for metabonomic analysis. ► Multivariate statistical methods for NMR data analysis. ► Quality assessment and authentication of extra virgin olive oil.

3.

Multivariate curve resolution: A review of advanced and tailored applications and challenges   Review Article Pages 28-36 C. Ruckebusch, L. Blanchet Graphical abstract Highlights ► MCR is nowadays a well-established and widespread methodology for mixture analysis. ► The analytical issues requiring advanced applications of MCR are reviewed. ► Attention is paid to the literature published the years 2008–2012.

Chemometrics

4.

NIR imaging spectroscopy for quantification of constituents in polymers thin films loaded with paracetamol   Original Research Article Pages 37-44 Guilherme L. Alexandrino, Ronei J. Poppi Graphical abstract Highlights ► NIR chemical imaging and chemometrics were used for studying thin films based drug delivery systems. ► Thin films were polymers mixtures of HPMC, PVP and PEG-400 loaded with the drug paracetamol. ► MCR-ALS provided initial biased results on quantification of polymers and additional calibration step was required. ► Three different strategies were tested to suppress the bias on the quantification by MCR-ALS. ► Parcetamol distribution in the thin films has direct correlation with the PVP and PEG, but inverse correlation with HPMC.

5.

Effects of supervised Self Organising Maps parameters on classification performance   Original Research Article Pages 45-53 Davide Ballabio, Mahdi Vasighi, Peter Filzmoser Graphical abstract Highlights ► We evaluated effects of SOMs parameters on classification and computational time. ► The study was conducted on eighteen real datasets. ► Significant parameters and their interactions on classification were highlighted. ► Optimal architectures to reduce the computational time of SOMs was proposed.

Electrochemistry

6.

Glassy carbon electrodes modified with gold nanoparticles for the simultaneous determination of three food antioxidants   Original Research Article Pages 54-62 Xiaoyun Lin, Yongnian Ni, Serge Kokot Graphical abstract Highlights ► A gold nanoparticles modified glassy carbon electrode (AuNPs/GCE) was constructed. ► The electrochemical mechanism of BHA, BHT and TBHQ at the AuNPs/GCE was studied. ► The oxidation products of BHA and TBHQ were found to be the same. ► First-derivative method was used to resolve the overlapped voltammograms. ► Synthetic antioxidants in food samples were analyzed.

7.

Novel electrochemical biosensor based on functional composite nanofibers for sensitive detection of p53 tumor suppressor gene   Original Research Article Pages 63-69 Xiaoying Wang, Xiaobing Wang, Xiaoning Wang, Fentian Chen, Kehui Zhu, Qian Xu, Meng Tang Graphical abstract Highlights ► A novel electrochemical p53 biosensor based on functional composite nanofibers (MWNTs–PA6–PPy) was developed. ► The MWNTs–PA6–PPy electrode with large specific surface area and good biocompatibility can be used to enhance stability, speed and sensitivity. ► The biosensor can detect 50fM wild type p53 sequence. ► The strategy could be extended to develop various sensors for the detection of many kinds of analytes.

8.

Sensitive voltammetric determination of paracetamol by poly (4-vinylpyridine)/multiwalled carbon nanotubes modified glassy carbon electrode   Original Research Article Pages 70-76 Hanieh Ghadimi, Ramin M.A.Tehrani, Abdussalam Salhin Mohamed Ali, Norita Mohamed, Sulaiman Ab Ghani Graphical abstract Highlights ► A P4VP/MWCNT modified glassy carbon electrode was fabricated and characterized. ► The electrode was useful for determination of paracetamol. ► At optimum conditions, ascorbic acid and uric acid did not interfere in the electrode activity. ► The electrode exhibited good sensitivity, reproducibility and stability. ► The electrode was used for the determination of paracetamol in formulation tablets and urine samples.

Mass Spectrometry

9.

Isotope pattern deconvolution-tandem mass spectrometry for the determination and confirmation of diclofenac in wastewaters   Original Research Article Pages 77-85 Ángel Castillo, Emma Gracia-Lor, Antoni Francesc Roig-Navarro, Juan Vicente Sancho, Pablo Rodríguez-González, J. Ignacio García Alonso Graphical abstract Highlights ► Isotope dilution with isotope pattern deconvolution (IPD) has been applied to LC–MS/MS. ► The procedure allows the determination of organic compounds without calibration graph. ► Diclofenac determination in wastewater showed the need of this methodology in LC–MS/MS. ► Confirmation was accomplished with routine transitions used in multiresidue analysis. ► IPD permits the minimal labeling of the analyte which minimizes isotopic effect.