Just Published: Biosensors & Bioelectronics

A new issue of this journal has just been published. To see abstracts of the papers it contains (with links through to the full papers) click here:

Biosensors & Bioelectronics
http://rss.sciencedirect.com/publication/science/5223

Selected papers from the latest issue:

1.

Combination of cascade chemical reactions with graphene-DNA interaction to develop new strategy for biosensor fabrication   Original Research Article Available online 1 March 2013 Xiaoli Zhu, Liya Sun, Yangyang Chen, Zonghuang Ye, Zhongming Shen, Genxi Li Highlights ► Combination of cascade chemical reactions with graphene-DNA interaction. ► A broader scope for the application of graphene in biosensing can be achieved. ► Development of electrochemical study on target-regulated graphene-DNA interaction. ► Glucose can be well detected with a superior detection limit and detection range.

2.

A sensitive gold nanoparticles sensing platform based on resonance energy transfer for chemiluminescence light on detection of biomolecules   Original Research Article Available online 1 March 2013 Guoxing Qin, Shulin Zhao, Yong Huang, Jing Jiang, Yi-Ming Liu Highlights ► A new aptamer chemiluminescence nanosensor was proposed. ► The design principle was based on CRET between ABEI and AuNPs. ► This design provides a new method for the preparation of chemiluminescence sensor. ► The nanosensor exhibited high sensitivity and selectivity for thrombin detection.

3.

Monitoring of dual bio-molecular events using FRET biosensors based on mTagBFP/sfGFP and mVenus/mKOκ fluorescent protein pairs    Available online 27 February 2013 Ting Su, Shaotao Pan, Qingming Luo, Zhihong Zhang Highlights ► This paper develops a new combination of fluorescent protein-based pairs for dual FRET imaging. ► These FRET pairs are spectrally compatible without the need of additional image correction. ► Simultaneous imaging of Src kinase activity and Ca2+signalling is achieved by dual FRET imaging

4.

Fabrication of a colorimetric biosensing platform for the detection of protein-DNA interaction   Original Research Article Available online 27 February 2013 Zonghuang Ye, Wei Zhang, Lili Liu, Guifang Chen, Zhongming Shen, Nandi Zhou Highlights ► A novel colorimetric biosening platform for the detection of protein-DNA interaction. ► Interaction between ERα/NF-κB and their corresponding binding sequences is studied. ► The biosensing platform is easy-operated, cost-effective and universal.

5.

Acetylcholinesterase biosensor for carbamate drugs based on tetrathiafulvalene–tetracyanoquinodimethane/ionic liquid conductive gels   Original Research Article Available online 27 February 2013 Lucian-Gabriel Zamfir, Lucian Rotariu, Camelia Bala Highlights ► The first biosensing application of TTF-TCNQ/ionic liquid gel. ► Highly sensitive AChE biosensor. ► Very low detection limits for eserine and neostigimine drugs.

6.

Ultrasensitive electrochemical immunoassay for squamous cell carcinoma antigen using dumbbell-like Pt-Fe3O4 nanoparticles as signal amplification   Original Research Article Available online 26 February 2013 Dan Wu, Haixia Fan, Yuyang Li, Yong Zhang, Huixin Liang, Qin Wei Highlights ► A sensitive nonenzymatic sandwich-type immunosensor for the detection of SCC-Ag is developed. ► The synergetic effect present in dumbbell-like Pt-Fe3O4 NPs improves the sensitivity. ► The immunosensor has a wide linear range, low detection limit and high selectivity and stability. ► The immunosensor has potential application in health detection and medical tests.

7.

Immobilization of glucose oxidase into a nanoporous TiO2 film layered on metallophthalocyanine modified vertically-aligned carbon nanotubes for efficient direct electron transfer   Original Research Article Available online 26 February 2013 Hui-Fang Cui, Kuan Zhang, Yong-Fang Zhang, Yu-Long Sun, Jia Wang, Wei-De Zhang, John H.T. Luong Highlights ► Glucose oxidase (GOD) was adsorbed into a nanoporous TiO2film. ► The TiO2film was layered on iron phthalocyanine (FePc)- vertically-aligned carbon nanotubes. ► The GOD electrode in neutral PBS exhibited a pair of well-defined redox peaks. ► FePc nanoparticles contributed to high enzyme loading and bioelectrocatalysis for glucose. ► Voltammetric and amperometric responses of the GOD electrode to glucose were unaffected by O2.

8.

Multiplexed electrochemical immunoassay of biomarkers using metal sulfide quantum dot nanolabels and trifunctionalized magnetic beads   Original Research Article Available online 26 February 2013 Dianping Tang, Li Hou, Reinhard Niessner, Mingdi Xu, Zhuangqiang Gao, Dietmar Knopp Highlights ► We introduce a new multiplexed voltammetric immunoassay protocol for simultaneous detection of multiple biomarkers. ► PAMAM dendrimer-metal sulfide quantum dot (QD) nanolabels were used as distinguishable molecular tags. ► Trifunctionalized magnetic beads were used as immunosensing probes.

9.

Label-free biosensor based on an electrical tracing-assisted silicon microring resonator with a low-cost broadband source   Original Research Article Available online 26 February 2013 Kyung Woo Kim, Junfeng Song, Jack Sheng Kee, Qing Liu, Guo-Qiang Lo, Mi Kyoung Park Highlights ► A noble electrical tracing-assisted dual-microring system was developed. ► An inexpensive broadband light source was used instead of a tunable laser. ► Label-free and specific detection of HER2. ► The new platform opens new opportunities for applications in portable POC devices.

10.

A deep-blue OLED-based biochip for protein microarray fluorescence detection    Available online 24 February 2013 Alessandro Marcello, Daniele Sblattero, Cristina Cioarec, Paolo Maiuri, Patrizia Melpignano Highlights ► Fluorescence-based point of care diagnosis requires cost effective optical sources. ► A novel deep-blue organic light-emitting diode was optimized for emission at 430nm. ► The OLED was tested on a protein microarray with good sensitivity and specificity. ► These results will be instrumental for the development of next generation point-of-care biochips.

11.

Detection of HLA-B⁎27 gene using a spectral plasmon resonance imaging system    Available online 24 February 2013 Yucong Yang, Lu Yuan, Xiangyi Fang, Xiaohui Liang, Fan Yang Highlights ► A new application of home developed SPR array biosensor system which can simultaneously measure 12 samples in parallel. ► An new effort for the detection of HLA-B*27 gene in clinical application.

12.

High-speed integrated optical logic based on the protein bacteriorhodopsin    Available online 24 February 2013 Anna Mathesz, László Fábián, Sándor Valkai, Daniel Alexandre, Paulo V.S. Marques, Pál Ormos, Elmar K. Wolff, András Dér Highlights ► An all-optical, nanosecond logical switch was realized. ► The active material in the integrated optical device was the protein bacteriorhodopsin. ► The device (a comparator) worked in the ternary logic mode. ► The results demonstrate the applicability of a biomaterial in information technology.

13.

Ionic-liquid-enhanced glucose sensing ability of non-enzymatic Au/graphene electrodes fabricated using supercritical CO2 fluid   Original Research Article Available online 24 February 2013 Jia-Wun Wu, Chueh-Han Wang, Yi-Chen Wang, Jeng-Kuei Chang Highlights ► Supercritical CO2can uniformly disperse Au nanoparticles on graphene and CNTs. ► The proposed electrodes show an improved electro-oxidation ability toward glucose. ► The Au/CNT shows a higher sensing current than that of the Au/graphene electrode. ► With ionic liquid (IL), the glucose detection currents at the electrodes increase. ► With IL, the sensitivity of Au/graphene becomes greater than that of Au/CNT.

14.

Multi-labeled functionalized C60 nanohybrid as tracing tag for ultrasensitive electrochemical aptasensing   Original Research Article Available online 24 February 2013 Jing Han, Ying Zhuo, Yaqin Chai, Ruo Yuan, Yun Xiang, Qiang Zhu, Ni Liao Highlights ► We design a novel sandwich-type aptasensor for sensitive detection of PDGF-BB. ► A supramolecular method is adopted for the synthesis of FC60NPs. ► The detection probe (Au@PB/FC60) exhibits excellent electrochemical behaviors. ► Amplification of electrochemical signal and noise reduction.